Neuromusculoskeletal Medicine (OMT)  |   October 2020
A Case of Resolved Vincristine-Induced Constipation Following Osteopathic Medicine in a Patient With Infantile Fibrosarcoma
Author Notes
  • From the Division of Hematology, Oncology, and Bone Marrow Transplant at Nationwide Children's Hospital in Columbus, Ohio (Drs Belsky and Setty) and Touro University College of Osteopathic Medicine in Vallejo, California (Dr Wolf). 
  • Financial Disclosures: None reported. 
  • Support: None reported. 
  •  *Address correspondence to Jennifer A. Belsky, DO, Division of Hematology, Oncology, and Bone Marrow Transplant, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205-2664. Email: Jenny.Belsky@gmail.com
     
Article Information
Osteopathic Manipulative Treatment / Pediatrics
Neuromusculoskeletal Medicine (OMT)   |   October 2020
A Case of Resolved Vincristine-Induced Constipation Following Osteopathic Medicine in a Patient With Infantile Fibrosarcoma
The Journal of the American Osteopathic Association, October 2020, Vol. 120, 691-695. doi:https://doi.org/10.7556/jaoa.2020.102
The Journal of the American Osteopathic Association, October 2020, Vol. 120, 691-695. doi:https://doi.org/10.7556/jaoa.2020.102
Abstract

Vincristine-induced constipation is a common side effect in pediatric oncology patients. We report the case of an infant with histologic diagnosis of infantile fibrosarcoma who developed significant constipation because of ongoing vincristine administration. She was treated with osteopathic manipulative treatment and had significant improvement in symptoms. She was able to stop her home lactulose bowel regimen without signs or symptoms of constipation. This case demonstrates the benefit of osteopathic manipulative treatment for chemotherapy-induced constipation as an effective and simple supportive care option without added adverse events.

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