Desai PM, Mbachi C, Mathew M, Attar B, Mba B. Psychogenic Adipsia Presenting as Recurrent Functional Vomiting and Hypernatremia. J Am Osteopath Assoc 2020;120(5):359–361. doi: https://doi.org/10.7556/jaoa.2020.055.
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Hypernatremia is caused by a disproportionate balance of inadequate free water relative to sodium level. Frequent causes of hypernatremia include renal or gastrointestinal fluid loss, hypothalamic injury, and endocrine abnormalities. The authors describe a rare case of hypernatremia that manifested secondary to psychogenic adipsia in a 46-year-old woman presenting with intractable vomiting. Her presenting symptoms and laboratory abnormalities resolved after treatment was initiated for major depression. This case highlights the need for a holistic approach when confronted with a case of unexplained hypernatremia.
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