OMT Minute  |   July 2019
Mesenteric Lift for Constipation in Cystic Fibrosis
Author Notes
  • From the Touro University College of Osteopathic Medicine-CA in Vallejo. 
  • Financial Disclosures: None reported. 
  • Support: This video was produced by Touro University College of Osteopathic Medicine-CA. 
  •  *Address correspondence to Kimberly Wolf, DO, 1310 Club Dr, Mare Island, Vallejo, CA 94592-1187. Email: kimberly.wolf@tu.edu
     
Article Information
Osteopathic Manipulative Treatment / Pulmonary Disorders
OMT Minute   |   July 2019
Mesenteric Lift for Constipation in Cystic Fibrosis
The Journal of the American Osteopathic Association, July 2019, Vol. 119, e36-e37. doi:10.7556/jaoa.2019.085
The Journal of the American Osteopathic Association, July 2019, Vol. 119, e36-e37. doi:10.7556/jaoa.2019.085
Cystic fibrosis is an autosomal recessive genetic disorder caused by a mutation in the cystic fibrosis transmembrane regulator (CFTR) gene.1 This gene codes for a protein that is an active transport channel for chloride across cell membranes and is involved in the regulation of mucus and fluid consistency across several systems, including the gastrointestinal tract.1 As the movement of water and salt across the cellular membranes is decreased, mucus produced by the gastrointestinal system thickens and the composition of gastrointestinal fluid is altered, leading to slow colonic transit and constipation.1 This condition, which often causes discomfort, abdominal pain, and abdominal distension in patients with cystic fibrosis, also increases the risk for serious complications such as bowel obstruction and bowel perforation.2 

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