Review  |   July 2019
Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Emerging Osteopathic Approach: A Narrative Review
Author Notes
  • From the Institute for Neuro Immune Medicine at the Dr Kiran C. Patel College of Osteopathic Medicine at Nova Southeastern University in Fort Lauderdale, Florida. 
  • Financial Disclosures: None reported. 
  • Support: None reported. 
  •  *Address correspondence to Christopher Larrimore, MSc, OMS IV, Nova Southeastern University Dr Kiran C. Patel College of Osteopathic Medicine, 3301 College Ave, Fort Lauderdale, FL 33314-7796. Email: cl1398@mynsu.nova.edu
     
Article Information
Neuromusculoskeletal Disorders
Review   |   July 2019
Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Emerging Osteopathic Approach: A Narrative Review
The Journal of the American Osteopathic Association, July 2019, Vol. 119, 446-455. doi:https://doi.org/10.7556/jaoa.2019.081
The Journal of the American Osteopathic Association, July 2019, Vol. 119, 446-455. doi:https://doi.org/10.7556/jaoa.2019.081
Abstract

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating syndrome of unknown origin, characterized by profound postexertional malaise and fatigue, unrefreshing sleep, cognitive impairments, immune dysfunction, pain, autonomic dysfunction, and neuroendocrine symptoms. Although ME/CFS is well documented within the medical literature, it remains difficult to diagnosis and manage. Some of the current challenges include an absence of diagnostic markers, differing diagnostic criteria, and an overall lack of awareness within the medical community. As a result, patients are often frustrated by the difficulties in acquiring a diagnosis and from the overall lack of available treatments. In an effort to increase awareness, this review discusses disease pathophysiology, clinical presentation, and treatment options, while also highlighting the benefits of an osteopathic approach.

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