Context: Just Say Know to Drugs! is a summer pharmacology enrichment program for high school students. First-year osteopathic medical students serve as teachers, introducing students to pharmacology while acquiring teaching skills.

Objective: To assess the effects of a pharmacology program on high school students and to understand the effects of teaching this program on first-year osteopathic medical students.

Methods: The influence of a pharmacology STEM (science, technology, engineering, and mathematics) enrichment program on high school students’ career interests and student teacher preparedness was determined by a pre- and posttest, as well as a postprogram survey.

Results: Data from all 37 participating high school students and 10 of 16 student teachers (medical students and undergraduate assistants) were evaluated in the study. Survey findings suggested that this STEM program increased student awareness and knowledge of pharmacology, osteopathic medicine, and scientific research. Furthermore, student teachers thought that they developed the necessary skills to communicate and educate populations with diverse science backgrounds and comprehension levels. The immersion of high school students in the scientific content significantly increased student awareness of pharmacology (paired t test, P<.0001).

Conclusion: The Just Say Know to Drugs! program delivered benefits for both high school students and student teachers.