Clearfield M, Davis G, Weiss J, Gayer G, Shubrook JH. Cardiovascular Disease as a Result of the Interactions Between Obesity, Climate Change, and Inflammation: The COCCI Syndemic. J Am Osteopath Assoc 2018;118(11):719–729. doi: https://doi.org/10.7556/jaoa.2018.157.
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Obesity and climate change conspire to create an environment in which subclinical vascular inflammation leads to progressive atherosclerosis, which contributes to the number 1 cause of global mortality: cardiovascular disease. The syndemic model requires 2 or more diseases or contributors to disease (such as obesity and climate change) clustering within a specific population in addition to the associated societal and social factors, ultimately creating an environment supportive of a greater adverse interaction. This article explores the syndemic of obesity and climate change as a driver for cardiovascular disease.
Abbreviations: ACC, American College of Cardiology; AHA, American Heart Association; ATP III, Adult Treatment Panel III; IDF, International Diabetes Federation.
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