This study has several limitations. First, we used a cross-sectional, correlational survey design to collect data. Therefore, generalizations cannot be made regarding changes or trends over time, directionality of influence, or cause-and-effect relationships. Second, a convenience sample of students from a single osteopathic medical school was used to collect data, thus limiting the ability to generalize findings to all medical students, including allopathic medical students. Multisite data collection from several US medical schools might have provided a more diverse sample of student respondents. Third, self-report questionnaires used for data collection can result in response bias, social desirability bias, and inaccuracies. Also, data collection occurred in some group settings, so even though participants were informed that completing the survey was strictly voluntary, they may have felt peer pressure to complete the survey. Fourth, the scale to measure knowledge was constructed by the researchers and not previously validated, and its reliability was not high (α=.40). Thus, results from the regression model regarding knowledge of HIT as a predictor should be taken with caution and tested in a future study with a more reliable measure. Fifth, there were several disadvantages of conducting research via online surveys, including limited respondent availability and willingness to respond.