With the rise in popularity of foam sclerotherapy, it benefits physicians and patients to understand the risks of neurologic sequelae after this procedure. Our patient did not have obvious risk factors for complications of the procedure; however, she had visual and neurologic disturbances shortly after the procedure. It may be beneficial, therefore, to monitor patients for any symptoms before discharge from the medical office. Because neurologic complications are relatively rare, screening all patients for PFO may not be justified; however, a discussion with patients about potential complications may be warranted. Educating patients on stroke signs and symptoms and contraindications such as a PFO as a part of informed consent, for example, should be communicated in case a patient has an undiagnosed PFO or another undiagnosed risk factor that could lead to complications from foam sclerotherapy.