Dickerman J. Gallstone formation associated with weight reduction. J Am Osteopath Assoc 1990;90(5):456. doi: 10.7556/jaoa.1922.214.171.1246.
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The author presents the case history of an obese patient in whom gallstones developed 5 months after she began a weight-loss program. Conservative management with chenodeoxycholic acid completely resolved cholelithiasis following four months of treatment. Gallstone-formation has traditionally been attributed to supersaturation of bile with cholesterol. However, the author proposes that the formation of gallstones may also be related to a change in gallbladder mechanics stimulated by dieting over an extended period. Recognition of this risk can lead to early diagnosis of gallstones, thus enhancing effective treatment by conservative methods.
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