Case Report  |   July 2018
Perplexing Rash: Challenges to Diagnosis and Management of Mycosis Fungoides
Author Notes
  • From the Department of Internal Medicine at the Keesler Medical Center at the Keesler Air Force Base in Biloxi, Mississippi (Dr Aun); the Department of Internal Medicine at the Regional Medical Center Bayonet Point in Hudson, Florida (Dr H. Patel); the Department of Internal Medicine at the St John Providence Health System in Detroit, Michigan (Dr K. Patel); the Department of Family Medicine at the Edward Via College of Osteopathic Medicine in Spartanburg, South Carolina (Dr Cashman); and the Department of Dermatopathology at Pathology Consultants, Inc, in Greenville, South Carolina (Dr Bailey). 
  • Financial Disclosures: None reported. 
  • Support: None reported. 
  • Disclaimer: The views expressed herein are those of the authors and do not necessarily reflect the official policy or position of the Department of the Air Force, the Department of Defense, the US Government, Edward Via College of Osteopathic Medicine, or Pathology Consultants, Inc. 
  •  *Address correspondence to Jonathan A. Aun, DO, Keesler Medical Center, Department of Internal Medicine, 301 Fisher St, Biloxi, MS 39534-2508. Email: jon.aun16@gmail.com
     
Article Information
Cardiovascular Disorders / Gastroenterology / Neuromusculoskeletal Disorders / Ophthalmology and Otolaryngology / Preventive Medicine / Arthritis
Case Report   |   July 2018
Perplexing Rash: Challenges to Diagnosis and Management of Mycosis Fungoides
The Journal of the American Osteopathic Association, July 2018, Vol. 118, 472-478. doi:10.7556/jaoa.2018.101
The Journal of the American Osteopathic Association, July 2018, Vol. 118, 472-478. doi:10.7556/jaoa.2018.101
Abstract

Mycosis fungoides is the most ubiquitous form of cutaneous T-cell lymphoma. Diagnosis is arduous, as early phases often resemble common inflammatory dermatoses. The principal histologic features of MF include medium to large-sized cerebriform mononuclear cells in single or small clusters in the epidermis. Treatment modalities are prodigious and relapses are common. The authors present a case of a 69-year-old man with mycosis fungoides, followed by a review of diagnostic modalities and phototherapeutic interventions for patients with this condition. According to literature reports, monochromatic excimer light therapy is the most advantageous and well-tolerated phototherapy modality for patients with early patch stage mycosis fungoides.

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