The Somatic Connection  |   January 2018
CSF Flow Has a Significant Respiratory Component
Author Notes
  • University of California, San Diego School of Medicine 
Article Information
The Somatic Connection   |   January 2018
CSF Flow Has a Significant Respiratory Component
The Journal of the American Osteopathic Association, January 2018, Vol. 118, 52-53. doi:10.7556/jaoa.2018.011
The Journal of the American Osteopathic Association, January 2018, Vol. 118, 52-53. doi:10.7556/jaoa.2018.011
Takizawa K, Matsumae M, Sunohara S, Yatsushiro S, Kuroda K. Characterization of cardiac- and respiratory-driven cerebrospinal fluid motion based on asynchronous phase-contrast magnetic resonance imaging in volunteers. Fluids Barriers CNS. 2017;14(1):25. doi:10.1186/s12987-017-0074-1 
Neuroscientists at Tokai University Schools of Medicine in Kanagawa, Japan, used innovative imaging technology and Fourier analysis to analyze cerebrospinal fluid (CSF) velocities at the foramen magnum and Sylvian aqueduct. The purpose of this study was to characterize the cardiac- vs respiratory-driven motion of CSF. The prevailing consensus has been that the cardiac cycle is the dominant force in CSF flow, but this research from Takizawa et al suggests a significant contribution from the respiratory cycle. 

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