Case Report  |   July 2017
Thrombocytopenia and Spontaneous Intracranial Hemorrhage After Olanzapine Therapy
Author Notes
  • From the Department of Family and Emergency Medicine at Aria – Jefferson Health Bucks County in Langhorne, Pennsylvania. 
  • Financial Disclosures: None reported. 
  • Support: None reported. 
  •  *Address correspondence to Maricel Dela Cruz, DO, MPH, Aria – Jefferson Health Bucks County, 380 N Oxford Valley Rd, Langhorne, PA 19047-8304. E-mail: mdelacruz78@gmail.com
     
Article Information
Cardiovascular Disorders / Neuromusculoskeletal Disorders / Psychiatry
Case Report   |   July 2017
Thrombocytopenia and Spontaneous Intracranial Hemorrhage After Olanzapine Therapy
The Journal of the American Osteopathic Association, July 2017, Vol. 117, 473-475. doi:10.7556/jaoa.2017.092
The Journal of the American Osteopathic Association, July 2017, Vol. 117, 473-475. doi:10.7556/jaoa.2017.092
Abstract

The use of atypical antipsychotics in the United States has increased over the past decade, since atypical antipsychotics such as olanzapine and clozapine were introduced. Of the adverse effects associated with olanzapine, bone marrow suppression is one of the most common, but spontaneous intracranial hemorrhage secondary to thrombocytopenia is rare. The present case report describes an 88-year-old man who presented with an intracranial hemorrhage after taking olanzapine for 2 weeks. This case emphasizes the importance of monitoring the potential adverse effects associated with olanzapine and other antipsychotics, especially in elderly patients.

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