David A. Simpson, Anne M. Pawlak, Louis Tegmeyer, Christopher Doig, Donald Cox. Paraneoplastic intestinal pseudoobstruction, mononeuritis multiplex, and sensory neuropathy/neuronopathy. J Am Osteopath Assoc 1996;96(2):132. doi: 10.7556/jaoa.19184.108.40.206.
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A patient with diffuse intestinal pseudo-obstruction consisting of gastric paresis and impaired small and large bowel motility, mononeuropathy multiplex, and sensory neuropathy/neuronopathy was found to have small-cell carcinoma of the lung. The clinical symptoms were thought to be consistent with paraneoplastic neuropathy, and high antineuronal and anti-calcium channel antibodies led to the diagnosis of small-cell carcinoma of the lung. Identification of paraneoplastic neuropathy is important, because early treatment may halt the progression of the underlying carcinoma.
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