Clinical Images  |   May 2017
Retroperitoneal Fibrosis
Author Notes
  • From the Departments of Internal Medicine (Dr Conard) and Medical Education (Dr Mancini) at the Lakeland Health Center in St. Joseph, Michigan. Dr Conard is a third-year resident. 
  • Financial Disclosures: None reported. 
  • Support: None reported. 
  •  *Address correspondence to Jennifer Conard, MBA, DO, 1234 Napier Ave, St. Joseph, MI 49085-2112. E-mail:
Article Information
Endocrinology / Gastroenterology / Imaging / Hypertension/Kidney Disease / Urological Disorders / Diabetes / Clinical Images
Clinical Images   |   May 2017
Retroperitoneal Fibrosis
The Journal of the American Osteopathic Association, May 2017, Vol. 117, 340. doi:10.7556/jaoa.2017.067
The Journal of the American Osteopathic Association, May 2017, Vol. 117, 340. doi:10.7556/jaoa.2017.067
A 50-year-old man with type 2 diabetes mellitus, nonalcoholic fatty liver disease, and sarcoidosis presented to the emergency department with lower abdominal pain for the past 3 months. Physical examination revealed suprapubic discomfort, back pain, stress-induced incontinence, abdominal distention, and scrotal swelling. A computed tomographic angiogram of the abdomen and pelvis showed progressive, circumferential, periaortic internal iliac soft tissue swelling (image A, arrow). Laboratory test results confirmed elevated levels of C-reactive protein and serum complement C3 and C4. A venacavogram showed high-grade infrarenal inferior vena cava stenosis (image B, arrow). The patient was admitted to the hospital and given 1 mg of intravenous methylprednisolone for 3 days. A stent was placed, and the patient was discharged 6 days later. Oral prednisone was prescribed, beginning at a dose of 60 mg and decreasing by 10 mg every 3 weeks. One month after discharge methotrexate was prescribed (5 mg every 12 hours, 1 time weekly) and the patient's symptoms improved. 
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