Clinical Images  |   March 2017
Recurrent Painful Calcium Pyrophosphate Arthropathy
Author Notes
  • From the Department of Internal Medicine at the Reading Health System in West Reading, Pennsylvania. 
  • Dr Carpenter is a third-year resident and Dr Juliano is a second-year resident. 
  •  *Address correspondence to Lisa Carpenter, DO, Reading Hospital, Department of Internal Medicine, 420 S 5th Ave, West Reading, PA 19611-2143. E-mail: lisa.carpenter@readinghealth.org
     
Article Information
Imaging / Neuromusculoskeletal Disorders / Pain Management/Palliative Care / Clinical Images
Clinical Images   |   March 2017
Recurrent Painful Calcium Pyrophosphate Arthropathy
The Journal of the American Osteopathic Association, March 2017, Vol. 117, 199. doi:10.7556/jaoa.2017.036
The Journal of the American Osteopathic Association, March 2017, Vol. 117, 199. doi:10.7556/jaoa.2017.036
A 69-year-old woman presented to her primary care physician with pain and decreased range of motion in her left knee for the past 5 days. She reported no history of trauma. The patient underwent an arthrocentesis and received a 1.5-mL injection of triamcinolone, which improved her pain and range of motion. She returned 9 months later with the same symptoms lasting for 3 days. Physical examination revealed decreased flexion and extension and fullness in the posterior joint space. Laboratory studies revealed a high erythrocyte sedimentation rate (63 mm/h) and C-reactive protein level (7.66 mg/dL). Plain film radiograph of the knee showed calcification in the popliteal fossa (image). Calcium pyrophosphate crystals were identified in the synovial fluid, and calcium pyrophosphate deposition disease was diagnosed. She was given a 1.2-mg dose of colchicine orally, followed by a 0.6-mg dose 6 hours later, which resolved her symptoms and improved her range of motion. 
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