Case Report  |   March 2017
Osteopathic Manipulative Treatment in the Management of Isaacs Syndrome
Author Notes
  • From the Department of Obstetrics and Gynecology at Good Samaritan Hospital in West Islip, New York (Dr Shanahan), the Department of Family Medicine at the St. Claire Regional Medical Center in Morehead, Kentucky (Dr Raines), the St. Mary Mercy Hospital in Livonia, Michigan (Dr Coggins), and the University of Pikeville Kentucky College of Osteopathic Medicine (Drs Moore, Carnes, and Griffin). Drs Shanahan and Coggins are first-year residents and Dr Raines is a second-year resident. This research was conducted while Drs Shanahan and Coggins were fourth-year students at The University of Pikesville Kentucky College and Dr Raines was an intern. 
  •  *Address correspondence to Laura Griffin, DO, University of Pikeville,Kentucky College of Osteopathic Medicine, 147 Sycamore St,Pikeville, KY 41501-9118. E-mail: lauragriffin@upike.edu.com
     
Article Information
Neuromusculoskeletal Disorders / Osteopathic Manipulative Treatment
Case Report   |   March 2017
Osteopathic Manipulative Treatment in the Management of Isaacs Syndrome
The Journal of the American Osteopathic Association, March 2017, Vol. 117, 194-198. doi:10.7556/jaoa.2017.035
The Journal of the American Osteopathic Association, March 2017, Vol. 117, 194-198. doi:10.7556/jaoa.2017.035
Abstract

Isaacs syndrome is a rare neuromuscular disorder characterized by chronic muscle stiffness, cramping, fasciculations, myokymia, and hyperhidrosis. Pathogenesis includes autoimmunity, paraneoplastic disorders, genetic predisposition, or toxin exposure. There is no known cure for Isaacs syndrome. This case report describes a patient who had been given the diagnosis of Isaacs syndrome and received osteopathic manipulative treatment to manage fascial and cranial dysfunctions and reduce nervous system hyperexcitability. Long-term decrease of myokymia and reduction of severity and frequency of exacerbations resulted.

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