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Supplement Article  |   November 1999
COX-2--specific inhibition: Implications for clinical practice
Article Information
Supplement Article   |   November 1999
COX-2--specific inhibition: Implications for clinical practice
The Journal of the American Osteopathic Association, November 1999, Vol. 99, S18-S22. doi:10.7556/jaoa.1999.99.11.S18
The Journal of the American Osteopathic Association, November 1999, Vol. 99, S18-S22. doi:10.7556/jaoa.1999.99.11.S18
Abstract

Although conventional nonsteroidal anti-inflammatory drugs (NSAIDs) have long been a major therapeutic choice for the management of arthritic conditions, the potential adverse effects of these agents sometimes compromise their clinical utility. New modes of therapy have recently been introduced, and data on the cyclooxygenase-2 (COX-2)-specific inhibitors celecoxib and rofecoxib suggest that these agents will meet the need for safe and effective therapeutic alternatives to conventional NSAIDs.