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Supplement Article  |   July 1999
Leukotriene modifiers in the management of asthma
Article Information
Supplement Article   |   July 1999
Leukotriene modifiers in the management of asthma
The Journal of the American Osteopathic Association, July 1999, Vol. 99, S1-S6. doi:10.7556/jaoa.1999.99.7.S1
The Journal of the American Osteopathic Association, July 1999, Vol. 99, S1-S6. doi:10.7556/jaoa.1999.99.7.S1
Abstract

Leukotrienes play a major role in the underlying pathophysiology of asthma. Leukotriene-receptor antagonists and direct leukotriene-synthesis inhibitors may be important new agents in maintenance therapy for asthma. Their role may also extend to attenuating exercise-induced and allergen-induced bronchospasm. This article reviews the effectiveness of available leukotriene modifiers in various clinical studies, reviews their adverse effects profile, and discusses their potential roles in the management of asthma.