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Case Report  |   September 1997
Update and review of blastomycosis
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Case Report   |   September 1997
Update and review of blastomycosis
The Journal of the American Osteopathic Association, September 1997, Vol. 97, 525. doi:10.7556/jaoa.1997.97.9.525
The Journal of the American Osteopathic Association, September 1997, Vol. 97, 525. doi:10.7556/jaoa.1997.97.9.525
Abstract

Blastomycosis has a wide spectrum of clinical presentations. When a patient presents with chronic pneumonia, especially coexisting with cutaneous lesions, blastomycosis infection needs to be considered in the differential diagnosis. Erythema nodosum can rarely be associated with pulmonary blastomycosis. A positive culture is the gold standard of diagnosis; occasionally, the organism can be identified by its typical "shoe print" morphology with periodic acid-Schiff (PAS) stain. The Gen-Probe technique may be required to confirm the uncertain culture results. The preferred treatment for blastomycosis in less severe cases is oral itraconazole, with amphotericin B in disseminated cases.