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Case Report  |   July 1993
Acute mastocytosis: a potential dermatologic emergency
Article Information
Case Report   |   July 1993
Acute mastocytosis: a potential dermatologic emergency
The Journal of the American Osteopathic Association, July 1993, Vol. 93, 792. doi:10.7556/jaoa.1993.93.7.792
The Journal of the American Osteopathic Association, July 1993, Vol. 93, 792. doi:10.7556/jaoa.1993.93.7.792
Abstract

A comatose patient arrived at the emergency room with apnea and in shock after a grand mal seizure. A maculopapular rash, not initially observed, led to a diagnosis of cutaneous mastocytosis. Degranulation of the mast cells with massive histamine release had resulted in cardiovascular collapse. The authors follow a detailed report of this case history with a discussion of the diagnosis and treatment of the acute systemic stage of this potentially life-threatening illness.