Markuly S, Fanning J, Hindman T, Galle P, Ertmoed E, Hilgers R. False-positive malignant peritoneal cytology associated with pelvic endometriosis. J Am Osteopath Assoc 1994;94(2):157. doi: 10.7556/jaoa.1918.104.22.168.
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The peritoneal washings obtained at diagnostic laparoscopy of two women with suspected endometriosis contained cells with cytologic features of adenocarcinoma. Exploratory laparotomy, total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and pelvic washings confirmed endometriosis with no evidence of cancer. At 1.5-year and 4.0-year follow-up, respectively, cancer had not developed in either patient. The authors report what they were able to find in the literature regarding false-positive assessments of malignancy obtained by cytologic examination. They also outline steps to be taken should a diagnosis of malignancy arise in a woman with endometriosis who desires pregnancy.
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