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Articles  |   July 1992
Therapeutic drug monitoring: lithium levels
Article Information
Articles   |   July 1992
Therapeutic drug monitoring: lithium levels
The Journal of the American Osteopathic Association, July 1992, Vol. 92, 907. doi:10.7556/jaoa.1992.92.7.907
The Journal of the American Osteopathic Association, July 1992, Vol. 92, 907. doi:10.7556/jaoa.1992.92.7.907
Abstract

Lithium has been used in the treatment of mania since 1949. Although its effectiveness is well recognized, the mechanism by which it stabilizes manic behavior is not well understood. In addition, it has some serious toxic properties combined with a narrow therapeutic range. For this reason, monitoring of serum lithium levels is mandatory. Suggested mechanisms of action and protocols for monitoring of serum levels are presented.