McCormick K. Thrombotic thrombocytopenic purpura. J Am Osteopath Assoc 1989;89(2):199. doi: 10.7556/jaoa.19188.8.131.52.
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Once formerly thought to be a rare disorder, thrombotic thrombocytopenic purpura (TTP) is becoming increasingly recognized. It is characterized by a pentad of clinical findings, including microangiopathic hemolytic anemia, thrombocytopenic purpura, neurologic and renal abnormalities, and fever. Following a case report, the major clinical findings, pathophysiologic findings, diagnoses, and use of various therapeutic modalities are discussed.
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