LT Sarah E. Broski, CAPT Dennis E. Amundson. Paradoxical Response to Levalbuterol. J Am Osteopath Assoc 2008;108(4):211–213. doi: 10.7556/jaoa.2008.108.4.211.
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Asthma is a common condition that can substantially affect patients' quality of life. Although several drugs, most commonly β-adrenergic agonists, alleviate symptoms of asthma, they may cause paradoxical bronchospasm or paradoxical bronchoconstriction. Levalbuterol hydrochloride—a pure form of the (R)-stereoisomer in racemic albuterol—eliminates the adrenergic properties that can cause such adverse effects. However, we report a case of paradoxical bronchoconstriction in a 36-year-old man who was recently diagnosed as having new-onset asthma and was treated with levalbuterol.
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